Ahead of Print | DOI: 10.14744/ejmo.2023.45210

Potential Value of the Motor Protein Family KIF as a Diagnostic & Prognostic Marker for Human Hepatocellular Carcinoma: A Prospective Research

Zhen Feng¹, Yong Lian¹, Yixuan Wang^2
1The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China, ²The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China,

Liver cancer is a common type of cancer with high mortality rates worldwide. Kinesin family (KIF) members are important molecular motors involved in various cellular processes, including cell division and intracellular transport. In this study, we conducted a comprehensive analysis of the expression of KIF family members in liver hepatocellular carcinoma (LIHC) using bioinformatics methods. We found that the expression levels of KIF family members, including KIF1C, KIF3B, KIF7, KIF9, KIF11, KIF14, and KIF18A, were generally higher in LIHC compared to normal tissues. The expression levels of KIF11 and KIF14 were closely related to the prognosis of LIHC, suggesting that they may be potential biomarkers for LIHC. Our findings provide important insights into the potential roles of KIF family members in LIHC and contribute to the identification of new biomarkers and therapeutic targets for the clinical treatment of liver cancer. Further experimental validation is needed to confirm our findings. Keywords: Biomarkers, clinical prognosis, KIF, LIHC

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Cite This Article

Feng Z, Lian Y, Wang Y. Potential Value of the Motor Protein Family KIF as a Diagnostic & Prognostic Marker for Human Hepatocellular Carcinoma: A Prospective Research. EJMO. ; (): -

Corresponding Author: Yong Lian