Potential Value of the Motor Protein Family KIF as a Diagnostic & Prognostic Marker for Human Hepatocellular Carcinoma: A Prospective Research
Zhen Feng1, Yong Lian1, Yixuan Wang21The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China, 2The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China,
Objective: To analyze the expression of Kinesin family (KIF) members in liver hepatocellular carcinoma (LIHC) using bioinformatics methods. Methods: Conducted a comprehensive analysis of KIF family member expression in LIHC. Utilized bioinformatics methods for data analysis. Results: The expression levels of KIF family members (KIF1C, KIF3B, KIF7, KIF9, KIF11, KIF14, and KIF18A) were generally higher in LIHC compared to normal tissues. The expression levels of KIF11 and KIF14 showed a significant correlation with the prognosis of LIHC. KIF11 and KIF14 may serve as potential biomarkers for LIHC. Conclusion: The study provides insights into the roles of KIF family members in LIHC. Identifies potential biomarkers (KIF11 and KIF14) and therapeutic targets for the clinical treatment of liver cancer. Further experimental validation is required to confirm these findings. Keywords: Biomarkers, clinical prognosis, KIF, LIHC
Cite This Article
Feng Z, Lian Y, Wang Y. Potential Value of the Motor Protein Family KIF as a Diagnostic & Prognostic Marker for Human Hepatocellular Carcinoma: A Prospective Research. EJMO. 2023; 7(3): 270-286
Corresponding Author: Yong Lian