Sarcomatoid Transformation of Chromophobe Renal Cell Carcinoma: An Unusual Pathology
Irene De La Parra1, Álvaro Serrano1, Roser Vives1, Juan Hermida1, Luis Ignacio Diez-Valladares2, Jerónimo Barrera3, José Antonio Cortés4, Pilar González-Peramato5, Ángel Gómez1, Jesús Moreno11Department of Urology, Health Research Institute, Clínico San Carlos Hospital, Complutense University, Madrid, Spain, 2Department of General Surgery, Clínico San Carlos Hospital, Madrid, Spain, 3Department of Radiology, Clínico San Carlos Hospital, Madrid, Spain, 4Department of Pathology, Clínico San Carlos Hospital, Madrid, Spain, 5Department of Pathology, University Hospital La Paz, Autónoma University, Madrid, Spain,
Dear Editor, We have carefully read the response from Val-Bernal et al.,[1] and we feel sorry for any inconvenience that we may have caused. The purpose of our study[2] was to deepen the rare histologic type of renal tumor which is the chromophobe renal cancer with sarcomatoid differentiation, its mode of presentation, imaging techniques, histopathological analysis, prognostic factors, and treatment. Because it is a subject discussed in the literature but with only a few patients described, as a visual way to simplify the low incidence of this pathology, we used the results published by Bian et al.[3] on a table and added our clinical cases. With this, we reflected on the most important prognostic factors, as described in the literature, and how they affected survival. It is unquestionable that those two cases cited in Val-Bernal et al. could have enriched this table, especially because of their detailed histopathological analysis. Akhtar et al.[4] presented a left renal tumor with anaplastic spindle cells with a high mitotic rate intermingled with poorly differentiated
Cite This Article
De La Parra I, Serrano Á, Vives R, Hermida J, Diez-Valladares L, Barrera J, et al. Sarcomatoid Transformation of Chromophobe Renal Cell Carcinoma: An Unusual Pathology. EJMO. 2022; 6(2): 192-193
Corresponding Author: Irene De La Parra