P-ISSN 2587-2400 | E-ISSN 2587-196X
EJMO. 2020; 4(1): 89-93 | DOI: 10.14744/ejmo.2020.81980

First Case of Topical 5-FU Therapy for Cutaneous Metastasis in a patient with Colon Cancer

Gulrayz Ahmed1, Sylvia Alarcon Velasco1, Layla Van Doren1, Muhammad Wasif Saif2
1Department of Hematology and Oncology, Tufts Medical Center, Massachusetts, USA, 2Northwell health Cancer Institute, New York, USA

Cutaneous metastasis from colon cancer is rare, occurs in less than 6% of patients and its associated with poor prognosis. Most often it presents in the abdomen, inguinal or perineal regions, supraclavicular area, and less commonly on the face, neck, scalp, and prior surgical sites. We present a case of a 41-year-old female with colon cancer who developed cutaneous metastases to the scalp, and was treated with topical 5-FU and radiation therapy. Treatment options for cutaneous metastases usually include systemic therapy, topical chemotherapy, surgical excision, or radiation. Our case is probably the first report who was treated with topical 5-FU in addition to radiation therapy. This treatment modality is easy to use and we would recommend clinical trials to be conducted to further study the use of topical 5-FU. Keywords: Adenocarcinoma, cutaneous metastasis, colon cancer, fluorouracil imiquimod, skin-directed treatment, synergy, synergy of topical and systemic treatments, topical treatment, 5-FU


Cite This Article

Ahmed G, Velasco S, Van Doren L, Saif M. First Case of Topical 5-FU Therapy for Cutaneous Metastasis in a patient with Colon Cancer. EJMO. 2020; 4(1): 89-93

Corresponding Author: Saif M.

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