Dosimetric Comparison of Adjuvant Pelvic Radiotherapy for Endometrial Cancer using Intensity-Modulated Radiotherapy (IMRT), Volumetric Modulated Arc Therapy (VMAT) and Helical Tomotherapy (HT)
Oztun Temelli1, Mehmet Demirtas1, Mahmut Serdar Sisecioglu2, Eda Kaya Pepele21Department of Radiation Oncology, Inonu University, Faculty of Medicine, Malatya, Turkey, 2Department of Radiation Oncology, Kayseri City Hospital, Kayseri, Turkey,
Objectives: The purpose of the present study is to compare dosimetrically IMRT, VMAT, HT techniques in endometrium cancer adjuvant radiotherapy practice. Methods: The 10 patients to whom we had applied Pelvic RT due to endometrium cancer previously were selected retrospectively. All patients had received TAH+BSO+BPLND. Three different plans were made for the patients as IMRT, VMAT, and HT. Results: The rectum V40 was found to be 53%, 54%, 45% (p=0.002), respectively; and the bladder V45 was 27%, 26%, 20% (p=0.002), respectively. Bowel V40 was found to be 15%,17%,12%, respectively (p=<0.001). Total monitor unit (MU) and beam-on times were found superior at VMAT (<0.001). Bone marrow V40 was found to be 27%, 26%, 33%, respectively (p<0.001). Conclusion: It was found that the three techniques were suitable in terms of planning criteria and OARs. HI and CI were found to be superior at HT. In risky organs, in rectum, bowel and bladder, HT was found to be superior than the others; in terms of bone marrow, IMRT was found to be superior; and in terms of bone, VMAT was found to be superior. VMAT has the advantage of having short treatment time and low MU. Keywords: Endometrial cancer,radiotherapy.
Cite This Article
Temelli O, Demirtas M, Sisecioglu M, Kaya Pepele E. Dosimetric Comparison of Adjuvant Pelvic Radiotherapy for Endometrial Cancer using Intensity-Modulated Radiotherapy (IMRT), Volumetric Modulated Arc Therapy (VMAT) and Helical Tomotherapy (HT). EJMO. 2019; 3(3): 203-210
Corresponding Author: Oztun Temelli