P-ISSN 2587-2400 | E-ISSN 2587-196X
EJMO. 2018; 2(3): 179-181 | DOI: 10.14744/ejmo.2017.37929

Effect of Alpha Lipoic Acid in the Treatment of Multiple Sclerosis-Induced Neuropathic Pain: A Case Report

Fazil Kulakli1
1Department of Physical Medicine and Rehabilitation, Giresun University Prof.Dr. İlhan Özdemir Training and Research Hospital, Giresun, Turkey

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) resulting in motor, sensory, and cognitive impairment. MS symptoms greatly affect the quality of life of patients with one of the most common symptom being pain. Neuropathic pain (NP) that develops secondary to demyelination, neuro-inflammation, and axonal damage in the CNS is the most distressing and difficult type of pain to treat in patients with MS. A patient with MS presented to our department with dysesthetic extremity pain that was characterized by burning and tingling predominantly in both feet and was worse at night. She was evaluated and diagnosed with MS-induced NP and treated with alpha lipoic acid (ALA) because of unresponsiveness and intolerance to amitriptyline, pregabalin, and gabapentin treatments. In this report, we present and discuss the ALA treatment in a patient with MS-induced NP.


Effect of Alpha Lipoic Acid in the Treatment of Multiple Sclerosis-Induced Neuropathic Pain: A Case Report. EJMO. 2018; 2(3): 179-181

Corresponding Author: Fazil Kulakli