Objectives: The present study was an investigation of the relationship between the hemogram parameters of mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), and the severity of stenosis observed in patients with coronary artery disease (CAD). Methods: A total of 240 patients, 163 with CAD (85 male, 78 female) and 77 controls with no stenosis were included in the study. Patients were divided into 3 groups based on their Gensini score. Results: It was determined that the mean MPV of the severe stenosis group and the mean NLR of the severe stenosis group were statistically significantly higher than in the control group (p=0.023, p=0.014). Conclusion: This study established an association between the Gensini score and the MPV, NLR, and PLR for the first time. The aim of this research was to assist with the early diagnosis of cardiovascular diseases. Regular recording and analysis of the MPV, NLR, and PLR of patients by family physicians can increase early detection and treatment, thereby decreasing morbidity and mortality.
Corresponding Author: Ozsari S.